The origin of a common compound about 100-48-1

At the same time, in my other blogs, there are other synthetic methods of this type of compound,100-48-1, Isonicotinonitrile, and friends who are interested can also refer to it.

100-48-1, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 100-48-1, name is Isonicotinonitrile. A new synthetic method of this compound is introduced below.

Reference Example 2: Synthesis of 4-(5-amino-1,2,4-oxadiazol-3-yl)pyridine. 17.1 g of 4-cyanopyridine, 70 ml of water, 11.4 g of hydroxylamine hydrochloride and 8.7 g of Na2CO3 were stirred in an autoclave for 8 hours with heating at 70C and, after cooling, the resulting reaction mixture was mixed with 60 ml of water, heated again and then spontaneously cooled to obtain 20.8 g of isonicotinamidoxime.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,100-48-1, Isonicotinonitrile, and friends who are interested can also refer to it.

Reference:
Patent; KATAYAMA SEIYAKUSYO CO. Ltd.; Ajinomoto Co., Inc.; EP641797; (1995); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem