Related Products of 1082040-63-8, Adding some certain compound to certain chemical reactions, such as: 1082040-63-8, name is 3-Iodo-1H-pyrazolo[3,4-c]pyridine,molecular formula is C6H4IN3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1082040-63-8.
B. Tert-butyl 2-(3-iodo-I H-pyrazolo[3,4-c]pyridi n-I -yI)acetateTo a suspension of 3-iodo-IH-pyrazolo[3,4-c]pyridine (6.24 g, 22.9 mmol) and potassium carbonate (7.29 g, 52.7 mmol) in CH3CN (50 mL) was added dropwise at RT tert-butyl 2- bromoacetate (4.06 mL, 27.5 mmol). The resulting mixture was refluxed for 2 h. The mixture was cooled to RT and filtered, the solid was washed with CH3CN and the filtrate was concentrated and purified by flash column chromatography on silica gel (c-hexane/EtOAc 4:1, then 2:1, then 1:1) to afford the title compound. MS (LC/MS): 360.0 [M+H]+; tR (HPLC conditions d): 2.93 mm.
According to the analysis of related databases, 1082040-63-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; NOVARTIS AG; ALTMANN, Eva; HOMMEL, Ulrich; LORTHIOIS, Edwige Liliane Jeanne; MAIBAUM, Juergen Klaus; OSTERMANN, Nils; QUANCARD, Jean; RANDL, Stefan Andreas; VULPETTI, Anna; WO2014/2051; (2014); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem