1122-54-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 1122-54-9, name is 4-Acetylpyridine, molecular formula is C7H7NO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
4-acetylpyridine (1.00 mL, 9.04 mmol) was added to a solution of HBr (47 % in 0, 4.56 mL, 27.12 mmol) in AcOH (20 mL) at 25 C. Bromine (1.59 g, 0.51 mL, 9.94 mmol) was added dropwise to the solution, then a white precipitate appeared slowly. The mixture was stirred for 20 h. Diethyl ether (20 mL) was added, the solid was filtered and washed with diethyl ether (2 x 5 mL). After drying under vacuum, 4-(2-bromoacetyl)pyridin-l-ium bromide was obtained as an off-white solid (2.529 g) which was used without further purification.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 1122-54-9, 4-Acetylpyridine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; MASARYKOVA UNIVERZITA; PARUCH, Kamil; CARBAIN, Benoit; HAVEL, Stepan; DAMBORSKY, Jiri; BREZOVSKY, Jan; DANIEL, Lukas; SISAKOVA, Alexandra; NIKULENKOV, Fedor; KREJCI, Lumir; (190 pag.)WO2019/201865; (2019); A1;,
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