Application of 115170-40-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 115170-40-6, name is 5-Bromo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine. This compound has unique chemical properties. The synthetic route is as follows.
A mixture of 1 (0.35 g, 1.76 mmol), 4-cyanobenzenesulfonyl chloride (0.39 g, 2.64 mmol), and pyridine (2 ml) was stirred at room temperature overnight. The reaction was quenched with water and the mixture was extracted with ethyl acetate (30ml*3). The organic layer was collected and dried over anhydrous MgS04, and concentrated in vacuo to yield a brown residue, which was purified by a flash column over silica gel (ethyl acetate: n-hexane = 1 : 1, Rf = 0.58) to afford 2n (0.35 g, 54.60%) as a yellow solid. *H-NMR (500MHz, CDC13): delta 3.09 (t, /= 8.5 Hz, 2H), 4.11 (t, /= 8.5 Hz, 2H), 7.50 (s, 1H), 7.79 (d, /= 8.5 Hz, 2H), 8.17 (s, 1H), 8.23 (d, /= 8.5 Hz, 2H).
According to the analysis of related databases, 115170-40-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; YEN, Yun; TAIPEI MEDICAL UNIVERSITY; NATIONAL HEALTH RESEARCH INSTITUTES; LIOU, Jing-Ping; CHANG, Jang-Yang; WANG, Jia-Yi; WO2015/157504; (2015); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem