Reference of 1211533-83-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1211533-83-3, name is 5-Bromo-6-methoxypyridin-2-amine. This compound has unique chemical properties. The synthetic route is as follows.
To a solution of 5-bromo-6-methoxypyridin-2-amine (50 mg, 246.2 umol) and 2- methylbenzene-l-sulfonyl chloride (70.4 mg, 369.3 umol, 53.3 uL) in DCM (3.0 mL) was added pyridine (58.4 mg, 738.7 umol, 59.6 uL), the mixture was stirred at 45C for 12 h. The reaction mixture was concentrated under reduced pressure to give a residue. The residue was purified by prep-TLC (Si02) to give N-(5-bromo-6-methoxypyridin-2-yl)-2-methylbenzenesulfonamide (80 mg, 208.2 umol, 84.5% yield). M+H+ = 359.1 (LCMS).
According to the analysis of related databases, 1211533-83-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; QUENTIS THERAPEUTICS, INC.; VACCA, Joseph P.; LI, Dansu; BETTIGOLE, Sarah; (184 pag.)WO2018/222918; (2018); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem