16063-70-0, Adding a certain compound to certain chemical reactions, such as: 16063-70-0, 2,3,5-Trichloropyridine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 16063-70-0, blongs to pyridine-derivatives compound.
40.0 g of 2,3,5-trichloropyridine was dissolved in 240 g of dimethyl sulfoxide.65.2 g of methyl cyanoacetate and 75.8 g of potassium carbonate were sequentially added to the reaction solution.The reaction was stirred at 120 C. for 7.5 hours.After completion of the reaction, the reaction solution was cooled to 40 C., and 200 g of water and 114 g of 35 mass% hydrochloric acid were added to the reaction solution.The reaction was stirred at room temperature for 1 hour.The solid precipitated in the reaction solution was separated by filtration.The obtained solid was washed sequentially with 50 g of water, 50 g of normal hexane, and 100 g of diisopropyl ether, and then dried under reduced pressure to obtain 41.8 g of the desired product as a yellow solid (yield: 77.7%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,16063-70-0, its application will become more common.
Reference:
Patent; Nissan Chemical Industries, Ltd.; Nakayama, Yosuke; Saito, Fumiyo; Nanju, Yusuke; (53 pag.)JP2019/34892; (2019); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem