In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 183483-29-6, name is 2-(2-Bromopyridin-4-yl)acetic acid, the common compound, a new synthetic route is introduced below. Product Details of 183483-29-6
2-(2-Bromopyridin-4-yl)acetic acid (5 g, 23.1 mmol), benzene (40.5 ml) and MeOH (5.8 ml) were added to a 250 mL flask, thentrimethylsilyldiazomethane (11.6 ml, 23.1 mmol, 2 M) was added dropwise over 5 mm. The reaction was concentrated in vacuo. Silica gel chromatography using a hexanes/EtOAc gradient (0-100%) afforded the title compound.
The synthetic route of 183483-29-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; MERCK SHARP & DOHME CORP.; HAN, Xiaoqing; WHITEHEAD, Alan; RAGHAVAN, Subharekha; GROEPER, Jonathan; GUO, Jian; ZHANG, Yong; WO2015/88885; (2015); A1;,
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