Application of 1160791-13-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1160791-13-8, name is 2-Amino-6-bromothiazolo[5,4-b]pyridine. This compound has unique chemical properties. The synthetic route is as follows.
To 6-bromothiazoio[5,4-b]pyridin-2-amine (1 .1 g, 4.8 mmol) in acetonitriie (92 mL) was added copper(ll)chloride (964 mg, 7.2 mmol) and the mixture was cooled to OX. Tert- butyl nitrite (739 mg, 7.2 mmol) in acetonitriie (46 mL) was added slowly and the mixture was stirred for 30 minutes at Omicron’ and addit ional 4 hours at room temperature. The mixture was diluted with ethyl acetate, washed with saturated NH4CI-solution, with saturated sodium bicarbonate solution, brine and water. Evaporation yielded 580 mg (47 %) 6-bromo-2-chlorothiazolo[5,4-b]pyridine NMR (300 MHz, DMSO-cfe) delta = 7.87 (d, 1 H), 8.36 (d, 1 H) ppm.
According to the analysis of related databases, 1160791-13-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; ROeHN, Ulrike; SCHMITT-WILLICH, Heribert; HEINRICH, Tobias; BERGER, Markus; FITZNER, Ansgar; KRAUSE, Sabine; BROCKSCHNIEDER, Damian; DYRKS, Thomas; THIELE, Andrea; MOeNNING, Ursula; BOeMER, Ulf; WO2012/7510; (2012); A1;,
Pyridine – Wikipedia,
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