Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 107351-82-6, name is 2-Bromo-5-phenylpyridine. This compound has unique chemical properties. The synthetic route is as follows. Product Details of 107351-82-6
General procedure: Intermediate M1 (43.6 g, 0.1 mol), iodobenzene (24.5 g, 0.12 mol), CuI (3.3 g, 17.1 mmol), K3PO4 (21.8 g, 102.9 mmol), ethylenediamine (2.3 ml, 34.3 mmol) and toluene (500 ml) were mixed.After stirring for 1 day under reflux, after the reaction was completed, it was cooled to room temperature, and the organic layer was extracted with ethyl acetate (EA) and distilled under reduced pressure. the obtained distillation residue was subjected to column separation (eluent: EA/hexane), compound A1 (35.7 g, 70.1%) was obtained.
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Reference:
Patent; Wuhan Shengchengyu Technology Co., Ltd.; Huang Yupeng; Qin Wei; Gao Dewen; Tan Yao; (19 pag.)CN109096281; (2018); A;,
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