Adding a certain compound to certain chemical reactions, such as: 483324-01-2, 2-Chloro-4-(pyridin-3-yl)pyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C9H6ClN3, blongs to pyridine-derivatives compound. Formula: C9H6ClN3
Preparation of 4-pyridin-3-yl-pyrimidin-2-ylamine lll-b In a sealed tube, a solution of lll-a (1 .18 g, 6.16 mmol) in 30percent NH4OH (12 mL) was heated at deltaOmicron ‘ for 16h. After cooling, the precipitate was isolated by filtration, washed with water and dried under vacuum to give the title compound lll-b as a beige solid (925 mg, 87 percent). H NMR (400 MHz, DMSO-d6) delta 9.23 (d, J = 2.1 Hz, 1 H), 8.69 (dd, J = 4.7, 1 .3 Hz, 1 H), 8.43 – 8.38 (m, 1 H), 8.36 (d, J = 5.1 Hz, 1 H), 7.53 (dd, J = 8.0, 4.8 Hz, 1 H), 7.21 (d, J = 5.1 Hz, 1 H), 6.76 (s, 2H).
The synthetic route of 483324-01-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; AB SCIENCE; MOUSSY, Alain; BENJAHAD, Abdellah; SCHALON, Claire; PEZ, Didier; CHEVENIER, Emmanuel; SANDRINELLI, Franck; MARTIN, Jason; PICOUL, Willy; WO2014/202763; (2014); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem