Synthetic Route of 169205-95-2, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.169205-95-2, name is 2-(Methylthio)oxazolo[4,5-b]pyridine, molecular formula is C7H6N2OS, molecular weight is 166.2, as common compound, the synthetic route is as follows.
To a solution of 2-(methylthio)oxazolo[4,5-b]pyri- dine (2.0 g, 12.12 mmol) in THF (5 mL) was added morpholine (5 mL) and heated at 75 C. overnight. The solvent was distilled off to afford the title compound (2.0 g, 83.3%).10210] ?HNMR (DMSO-d5, 300 MHz): oe 8.20-8.10 (d,1H), 7.80-7.70 (d, 1H), 7.15-7.00 (m, 1H), 3.75-3.72 (m,4H), 3.63-3.52 (m, 4H). LCMS: mlz: 206.5 (M+1)+
The chemical industry reduces the impact on the environment during synthesis 169205-95-2, I believe this compound will play a more active role in future production and life.
Reference:
Patent; AURIGENE DISCOVERY TECHNOLOGIES LIMITED; Gummadi, Venkateshwar Rao; Samajdar, Susanta; (82 pag.)US2016/340366; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem