Related Products of 1137-67-3, Adding some certain compound to certain chemical reactions, such as: 1137-67-3, name is 2-(Pyridin-3-yl)-1H-benzo[d]imidazole,molecular formula is C12H9N3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1137-67-3.
General procedure: To a stirred solution of 40 mg (0.18 mmol) of 2-[2-(pyridin-3-yl)ethyl]-1H-benzimidazole (2o) in N,N-dimethylformamide (5 mL) were added 71 mg (0.22 mmol) of 3-[4-(3-acetamidophenyl)piperidin-1-yl]propyl methanesulfonate (6) and 75 mg (0.54 mmol) of K2CO3. The reaction mixture was stirred at 80 C for 5 h. After cooling, water (50 mL) was added, and the mixture was extracted with ethylacetate (50 mL × 2). The organic layer was washed with brine, dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (5% MeOH/CH2Cl2) to obtain the title compound (75 mg, 87%).
According to the analysis of related databases, 1137-67-3, the application of this compound in the production field has become more and more popular.
Reference:
Article; Lim, Chae Jo; Kim, Jeong Young; Lee, Byung Ho; Oh, Kwang-Seok; Yi, Kyu Yang; Bulletin of the Korean Chemical Society; vol. 34; 8; (2013); p. 2305 – 2310;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem