Related Products of 18677-48-0, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 18677-48-0, name is 3,5-Dimethoxypyridine, molecular formula is C7H9NO2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
3,5-dimethoxypyridine of structure 1 (1.4 g, 10 mmol, 1.0 equiv.) was dissolved in tetrahydrofuran(30 mL), cooled to -78 C, add n-butyllithium (n-BuLi) (2.5M n-hexane solution, 4.8mL, 12mmol, 1.2equiv.), Stir for five minutes and add 1,1,2,2-tetrabromoethane (1.75 mL, 15 mmol, 1.5 equiv.). Return to room temperature. Post-processing, purification by silica gel column gave 1.14 g of 4-bromo-3,5-dimethoxypyridine 2 in a yield of 52%.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 18677-48-0, 3,5-Dimethoxypyridine.
Reference:
Patent; Chongqing University; Li Yang; Chen Di; (11 pag.)CN109836446; (2019); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem