Synthetic Route of 74115-13-2, Adding some certain compound to certain chemical reactions, such as: 74115-13-2, name is 5-Bromo-3-pyridinol,molecular formula is C5H4BrNO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 74115-13-2.
To a solution of NaOH (2.40 g, 1 15 mmol) in water (96mL) was added 5- bromopyridin-3-ol (10. Og, 57.5 mmol), followed by NaOCI aq. solution (60 ml of 10% solution). The reaction mixture was stirred at rt for 16 hours and then quenched with acetic acid (7 ml). The precipitate was isolated by filtration and washed with water (200 mL). After drying under high vacuum, 7.0 g of product was obtained (59%). 1H NMR (400 MHz, DMSO d6): 1 1 .36 (s, 1 H), 8.01 (d, J = 2.1 Hz, 1 H), 7.50 (d, J = 2.2 Hz, 1 H).
According to the analysis of related databases, 74115-13-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; NOVARTIS AG; FU, Jiping; JIN, Xianming; LEE, Patrick; LU, Peichao; YOUNG, Joseph Michael; (76 pag.)WO2018/47109; (2018); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem