The origin of a common compound about 5-Nitro-1H-pyrazolo[3,4-b]pyridine

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 63572-73-6, 5-Nitro-1H-pyrazolo[3,4-b]pyridine, other downstream synthetic routes, hurry up and to see.

Reference of 63572-73-6, Adding some certain compound to certain chemical reactions, such as: 63572-73-6, name is 5-Nitro-1H-pyrazolo[3,4-b]pyridine,molecular formula is C6H4N4O2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 63572-73-6.

Compound 1 (2 g, 12.2 mmol, 1.0 eq),Soluble in DMF (20mL),NBS (2.5 g, 14.0 mmol, 1.15 eq) was added in portions at 0 C.The reaction was carried out for 16 hours at room temperature.LCMS showed the reaction of the starting material,There is product generation. Concentrate and spin dry to a crude product.Purified by column (PE/EA=100:1-10:1),Yellow solid compound 2 (1.4 g, yield: 94%).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 63572-73-6, 5-Nitro-1H-pyrazolo[3,4-b]pyridine, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Nanjing Kefeipingshenghui Pharmaceutical Co., Ltd.; Jin Qiu; Qin Yinlin; Su Mei; Qiu Yanan; Lou Yajing; (23 pag.)CN109206401; (2019); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem