Related Products of 52605-97-7, Adding some certain compound to certain chemical reactions, such as: 52605-97-7, name is 2,3-Dimethoxypyridine,molecular formula is C7H9NO2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 52605-97-7.
(c). 5-bromo-2,3-dimethoxypyridine To a solution of 2,3-dimethoxy-pyridine (104 g) in DCM (1 L) and a saturated aqueous solution of NaHC03 (1 .6 ml) at 0C was added bromine (120 g). The reaction was stirred for 2 hours at 0C. The reaction mixture was quenched with Na2S03 (saturated in water, 500 ml) and stirred for 30 min. The aqueous layer was extracted with DCM, and the organic phase was washed with brine, dried over Na2S04, filtered and concentrated. The crude product was purified by chromatography on silica gel with heptane and increasing amouts of ethyl acetate. Yield: 100 g 1H NMR delta (ppm)(CHCI3-d): 7.70 (d, 1 H, J=2.0 Hz), 7.06 (s, 1 H, J=2.0 Hz), 3.92 (s, 3H), 3.80 (s, 3H).
According to the analysis of related databases, 52605-97-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; MSD OSS B.V.; BLACKABY, Wesley, Peter; DE KORT, Martin; ENTHOVEN, Mark; HINCHLIFFE, Paul, Stuart; PAULIE, Chris; TIMMERS, Cornelis, Marius; VERKAIK, Saskia; WO2013/41458; (2013); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem