Synthetic Route of 52718-95-3, Adding some certain compound to certain chemical reactions, such as: 52718-95-3, name is Methyl 2-bromonicotinate,molecular formula is C7H6BrNO2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 52718-95-3.
Intermediate [1-B] (1.5 eq), methyl-2-bromoicotinate (1.1 eq), CuI (0.03 g), K2CO3 (2.0 eq), and L-Proline (0.04 eq) were dissolved in toluene (0.1 M) and stirred at a temperature of 130 i for 12 hours. After the reaction mixture was cooled to room temperature, and an organic layer was dried by using magnesium sulfate and concentrate, and column chromatography was used to obtain Intermediate [1-C] (yield: 59%).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 52718-95-3, Methyl 2-bromonicotinate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Samsung Display Co., Ltd.; KANG, Sunwoo; JEON, Sangho; CHO, Youngmi; (80 pag.)US2020/168817; (2020); A1;,
Pyridine – Wikipedia,
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