Adding a certain compound to certain chemical reactions, such as: 65938-77-4, 5-Methyl-2-pyridinesulfonamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Product Details of 65938-77-4, blongs to pyridine-derivatives compound. Product Details of 65938-77-4
To a mixture of 5-methylpyridine-2-sulfonamide (109 mg, 0.63 mmol) in 1 M aqueous NaOH (0.63 mL, 0.63 mmol) was added tert-butyl hypochlorite (86 uL, 0.76 mmol) and the reaction stirred at room temperature for 1 .5h in the dark. The reaction was evaporated and the desired product washed with diethyl ether and dried under reducedpressure to yield the crude product. Used in the next step without further purification. It was assumed that the reaction gave quantitative yield. LCMS m/z 207 [M+H] – Na.
The synthetic route of 65938-77-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; GLACTONE PHARMA DEVELOPMENT AB; JOHANSSON, Martin; STERNER, Olov; (84 pag.)WO2018/104295; (2018); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem