The origin of a common compound about 6854-07-5

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 6854-07-5, name is 5-Nitro-2-oxo-3-pyridinecarboxylic Acid. This compound has unique chemical properties. The synthetic route is as follows. name: 5-Nitro-2-oxo-3-pyridinecarboxylic Acid

Reference Example 11 Dimethylformamide (4 drops) was added to a solution of 2-hydroxy-5-nitronicotinic acid (5g) in phosphorus oxychloride (10ml). The mixture was stirred at the reflux temperature for 3 hours. Excess solvent was removed by evaporation and the residue was then poured carefully into water, keeping the temperature of the resulting mixture at below 40oC. The mixture was stirred at room temperature for a further 30 minutes then extracted with ethyl acetate. The extracts were washed with water, dried (magnesium sulphate) and evaporated. The resulting residue was triturated with ether/hexane to yield 2-chloro-5-nitronicotinic acid as a pale yellow solid (3.6g), m.p. 123-7oC.

With the rapid development of chemical substances, we look forward to future research findings about 6854-07-5.

Reference:
Patent; RHONE POULENC AGRICULTURE LTD.; EP634413; (1995); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem