The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 846021-26-9, name is 2-Amino-6-methylnicotinic acid. This compound has unique chemical properties. The synthetic route is as follows. Formula: C7H8N2O2
Production example 63 A mixture of 0.27 g of 4-(3-methoxyphenoxy)benzylamine, 0.15 g of 2-amino-6-methylnicotinic acid, 0.15 g of 1-hydroxybenzotriazole, 0.25 g of WSC, 0.35 g of pyridine and 2 ml ofDMF was stirred under heating to reflux for 30 minutes, and then at a room temperature for 1 day. Thereafter, water was added to the reaction mixture, and the precipitated solid was collected by filtration. The obtained solid was successively washed with a sodium bicarbonate aqueous solution, water, MTBE and hexane, and it was then dried, so as to obtain 0.25 g of N-[4-(3-methoxyphenoxy)phenyl]methyl-2-amino-6-methylnicotinic acid amide (hereinafter referred to as the present compound 79).The present compound 79 [Show Image] 1H-NMR (CDCl3) delta: 2.38 (3H, s), 3.78 (3H, s), 4.56 (2H, d, J = 5.6 Hz), 6.24 (1H, br s), 6.38 (2H, br s), 6.44 (1H, d, J = 7.7 Hz), 6.53-6.68 (3H, m), 7.00 (2H, d, J = 8.7 Hz), 7.20-7.25 (1H, m), 7.28-7.32 (2H, m), 7.49 (1H, d, J = 7.7 Hz).
With the rapid development of chemical substances, we look forward to future research findings about 846021-26-9.
Reference:
Patent; Sumitomo Chemical Company, Limited; EP2248423; (2010); A1;,
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