Adding a certain compound to certain chemical reactions, such as: 85148-95-4, 6-Formylpicolinonitrile, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 85148-95-4, blongs to pyridine-derivatives compound. name: 6-Formylpicolinonitrile
(a) 2-Amidino-6-formylpyridine hydrochloride 2-Cyano-6-formylpyridine (16.5 g =0.125 mol) is dissolved in 150 ml of dry ether and 150 ml of absolute ethanol, and the solution is saturated at 0° with dry hydrochloric acid gas and left to stand at 0° for 44 hours. The reddish brown reaction solution is concentrated to dryness. In order to remove excess hydrochloric acid, the residue is re-dissolved in absolute ethanol, concentrated by evaporation again and finally dried under a high vacuum. The resulting crude imino ether is dissolved in 100 ml of absolute ethanol, and a saturated ethanolic ammonia solution (100 ml) is added thereto. The reaction mixture is heated under reflux for 3 hours, cooled, filtered until clear and the filtrate is concentrated by evaporation. The solution of the residue in 100 ml of 2N hydrochloric acid is washed with ether, concentrated to dryness by evaporation and dried under a high vacuum. The title compound is obtained in crude form which is further processed direct.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,85148-95-4, its application will become more common.
Reference:
Patent; Ciba-Geigy Corporation; US4971986; (1990); A;; ; Patent; Ciba-Geigy Corporation; US5238941; (1993); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem