Adding a certain compound to certain chemical reactions, such as: 942189-65-3, 2-(6-Bromopyridin-3-yl)pyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 942189-65-3, blongs to pyridine-derivatives compound. SDS of cas: 942189-65-3
Example 31 To a stirred solution of 10 (3.05g, 12.9 mmol) in DMF (30 mL) 1 (5.97 mL, 38.7 mmol) and DIPEA (8.5 mL, 51.7 mmol) was added. The clear mixture was heated at 80 C overnight before concentrated to a small volume and partitioned between ethyl acetate and brine. The separated organic layer was dried and concentrated to dryness. The resulting crude was purified on silica gel column (eluting with 15% to 30% ethyl acetate in hexanes) to yield 11 as a brown solid (4.5 g, 84%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,942189-65-3, its application will become more common.
Reference:
Patent; SCHERING CORPORATION; ZHU, Hugh, Y.; DESAI, Jagdish, A.; COOPER, Alan, B.; DOLL, Ronald, J.; WO2011/41152; (2011); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem