In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 868551-30-8, name is Methyl 4-methyl-5-nitropicolinate, the common compound, a new synthetic route is introduced below. HPLC of Formula: C8H8N2O4
Methyl 4-[(1E)-2-(dimethylamino)ethenyl]-5-nitro-2-pyridinecarboxylate (0628) (0629) 86.4 g (0.73 mmol) of 18 N,N-dimethylformamide O,O-dimethyl acetal were added to a solution of 65 g (0.33 mol) of 19 methyl 5-methyl-6-nitro-3-pyridinecarboxylate (Y. Morisawa et al., J. Med. Chem. 21, 194-199, 1978) in 415 ml of 20 N,N-dimethylformamide. The reaction mixture was then stirred at 90 C. for 6 hours. The solvent was then removed under reduced pressure and the residue that remained was purified by column chromatography. This gave 56 g (yield 66.7% of theory) of 21 methyl 4-[(1E)-2-(dimethylamino)ethenyl]-5mitro-2-pyridinecarboxylate.
The synthetic route of 868551-30-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Bayer CropScience Aktiengesellschaft; JESCHKE, Peter; ARLT, Alexander; CEREZO-GALVEZ, Silvia; VOERSTE, Arnd; FUESSLEIN, Martin; FISCHER, Reiner; BRETSCHNEIDER, Thomas; ILG, Kerstin; MALSAM, Olga; LOESEL, Peter; GOERGENS, Ulrich; (74 pag.)US2017/325458; (2017); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem