Reference of 77837-09-3, Adding some certain compound to certain chemical reactions, such as: 77837-09-3, name is Methyl 6-oxo-1-phenyl-1,6-dihydropyridine-3-carboxylate,molecular formula is C13H11NO3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 77837-09-3.
After 750 mg (3.27 mmol) of methyl 6-oxo-1-phenyl-1,6-dihydro-3-pyridinecarboxylate was dissolved in 9 mL of methanol and 3 mL of water, 235 mg (9.81 mmol) of lithium hydroxide was added to the solution. Afterward, the resulting reaction solution was stirred at about 50C for about 5 hours. After termination of the reaction was determined by liquid chromatography, the solvent was removed in vacuo, followed by addition of aqueous HCl to titrate a pH of the reaction product to pH 2. After filtration of the resulting solid compound (Actual yield: 470 mg, Percent yield: 67 %), the resulting compound was used without purification.[60] 1H-NMR(DMSO-d6,200MHz)delta8.18(s,1H),7.88(d,1H),7.49(m,5H),6.54(d,2H)
According to the analysis of related databases, 77837-09-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; SK BIOPHARMACEUTICALS CO., LTD.; MAENG, Cheol Young; JANG, Young Koo; CHA, Su Bong; SHIN, Hye Won; JOUNG, Chan Mi; CHA, Hwa Ryun; YI, Eun Jung; WO2012/102580; (2012); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem