Adding a certain compound to certain chemical reactions, such as: 626-64-2, Pyridin-4-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 626-64-2, blongs to pyridine-derivatives compound. Recommanded Product: 626-64-2
1,7-dibromo perylene diimide (7, 56 mg, 0.1 mmol) was dissolved into 5 mL of DMF. To which 4-hydroxypyridine (47.6 mg, 0.5 mmol) and potassium carbonate (K2CO3, 70 mg, 0.5 mmol) were added. The resulted mixture was then allowed reacted under 80C for 1 hours. The reaction mixture was then powered into 50 mL of water and the red solid was then re-dissolved in 50 mL DCM and washed with 50 mL of 1N hydrochloric acid and then 50 mL of water each for 3 times. Then, DCM layer was dried over Na2SO4. After removal of DCM, the residue was applied to chromatography with CH2Cl2/ethyl acetate (100:0-100:2) as eluents to afford the desired products 9 as red solid (68.7 mg, 0.93 mmol, yield = 93%). 1H-NMR (400MHz, CDCl3) d ppm: 8.66 (s, 1H), 8.63 (s, 1H), 8.56 (d, J = 8.00 Hz, 2H), 7.60 (m, J = 8.00 Hz, 5H), 7.44 (d, J = 7.20 Hz, 1H), 6.69 (d, J = 8.00 Hz, 4H), 5.01 (t, 2H), 2.53 (q, J = 10.32 Hz, 4H), 1.93 (d, J = 10.00 Hz, 4H), 1.75 (d, J = 10.32 Hz, 6H), 1.48 -1.32 (m, J = 13.2 Hz, 12.00 Hz, 10.60 Hz, 11.60 Hz, 11.72 Hz, 6H). 13C-NMR (100 MHz, CDCl3) d ppm: 163.7, 163.4, 162.9, 155.5, 152.7, 152.5, 148.4, 148.3, 133.4, 130.2, 129.1, 128.7, 127.7, 126.5, 125.0, 123.8, 123.7, 123.6, 122.6, 122.1, 119.5, 119.3, 114.9, 59.6, 59.4, 30.8, 30.6, 26.1, 25.9, 24.5, 24.3. TOF MS: m/z = 740.2 [M+H]+.
The synthetic route of 626-64-2 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Zhang, Xin; Pang, Shufeng; Zhang, Zhigang; Ding, Xunlei; Zhang, Shanlin; He, Shenggui; Zhan, Chuanlang; Tetrahedron Letters; vol. 53; 9; (2012); p. 1094 – 1097;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem