SDS of cas: 500-22-1. In 2020.0 ORG LETT published article about PHOSPHINE-PHOSPHITE LIGANDS; CHEMISTRY; OLEFINS; STEREOCHEMISTRY; INTERCONVERSION; DERIVATIVES; MECHANISM; NITRILES; ALKENES in [Frye, Nils L.; Bhunia, Anup; Studer, Armido] Westfalische Wilhelms Univ, Organ Chem Inst, D-48149 Munster, Germany in 2020.0, Cited 45.0. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1.
Hydrocyanation in the absence of toxic HCN gas is highly desirable. Addressing that challenge, transition-metal-catalyzed transfer hydrocyanation using safe HCN precursors has been developed, but these reagents generally require a Lewis acid for activation, and the control of regioselectivity often remains problematic. In this Letter, a Ni-catalyzed highly Markovnikov-selective transfer hydrocyanation that operates in the absence of any Lewis acid is reported. The readily prepared pro-aromatic 1-isopropylcyclohexa-2,5-diene-1-carbonitrile is used as the HCN source, and the reaction shows a broad substrate scope and high functional group tolerance. Terminal styrene derivatives, dienes, and internal alkynes are converted with good to excellent selectivities. Mechanistic studies provide insights into the origin of the regioselectivity.
SDS of cas: 500-22-1. Welcome to talk about 500-22-1, If you have any questions, you can contact Frye, NL; Bhunia, A; Studer, A or send Email.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem