Tong, Xiaogang; Shi, Bingfei; Liu, Qian; Huo, Yanman; Xia, Chengfeng published the artcile< Retro-biosynthetic construction of corynanthe alkaloid skeletons from rhynchophylline alkaloids>, Quality Control of 93-60-7, the main research area is retro biosynthetic Wagner Meerwein rearrangement rhynchophylline corynanthe alkaloid.
Rhynchophylline alkaloids are bio-synthesized from corynanthe alkaloids via an oxidative rearrangement. We demonstrate here that corynanthe alkaloids could be generated from rhynchophylline alkaloids in a retro-biosynthetic manner via a Wagner-Meerwein rearrangement [e.g., I → II (85%) in presence of TFA in DCM]. A series of corynanthe analogs were afforded with good functional group tolerance and satisfactory yields.
Organic & Biomolecular Chemistry published new progress about Biomimetic synthesis (retro-biomimetic). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Quality Control of 93-60-7.