Troschuetz, Reinhard; Karger, Alexander published the artcile< Versatile synthesis of 6-substituted 8-deazapteridine-2,4-diamines. Formal total synthesis of 8,10-dideazaminopterin>, HPLC of Formula: 21901-29-1, the main research area is deazapteridinediamine preparation; dideazaaminopterin formal total synthesis.
A new synthesis of 4-amino-4-deoxy-8,10-dideazapteroic acid (I, R =CH2CH2C6H4CO2H-4, R1 = H) and 6-substituted and 5,6-anelated 8-deazapteridine-2,4-diamines I [R = Me, CH2CH2C6H4CO2Me-4, R1 = H; RR1 = (CH2)4] is described. Starting from (H2N)2C:CHNO2 or (H2N)2C:CHCO2Et and RCOCR1:CHNMe2, I can be prepared via functional group transformation of 2-aminopyridines yielding 3-amino-α-picolinonitriles which are cyclocondensed with guanidine.
Journal of Heterocyclic Chemistry published new progress about 21901-29-1. 21901-29-1 belongs to class pyridine-derivatives, and the molecular formula is C6H7N3O2, HPLC of Formula: 21901-29-1.