Pyridine-directed carbon-carbon single bond activation: Rhodium-catalyzed decarbonylation of aryl and heteroaromatic ketones was written by Wagner, Cole J.;Salisbury, Eric A.;Schoonover, Erik J.;VanderRoest, Jacob P.;Johnson, Jeffrey B.. And the article was included in Tetrahedron Letters in 2021.Category: pyridine-derivatives This article mentions the following:
The decarbonylation of 2-pyridyl-substituted ketones via transition metal-catalyzed carbon-carbon bond activation provided ready access to a variety of biaryl compounds The highly efficient and general method provided reliable decarbonylation of benzophenones including a range of functional groups and substitution patterns. The methodol. has also proven highly efficient for heteroaromatic substrates, including those containing thiophenyl, indolyl, quinolinyl and pyridine substitution. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Category: pyridine-derivatives).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Category: pyridine-derivatives