COA of Formula: C7H9NOIn 2019 ,《Merging Photochemistry with Electrochemistry: Functional-Group Tolerant Electrochemical Amination of C(sp3)-H Bonds》 appeared in Angewandte Chemie, International Edition. The author of the article were Wang, Fei; Stahl, Shannon S.. The article conveys some information:
A combined electrochem./photochem. method for dehydrogenative C(sp3)-H/N-H coupling that exhibits good reactivity with both sp2 and sp3 N-H bonds has been reported. The results show how use of iodide as an electrochem. mediator, in combination with light-induced cleavage of intermediate N-I bonds, enables the electrochem. process to proceed at low electrode potentials. This approach significantly improves the functional-group compatibility of electrochem. C-H amination, for example, tolerating electron-rich aromatic groups that undergo deleterious side reactions in the presence of high electrode potentials. The experimental process involved the reaction of 2-(2-Hydroxyethyl)pyridine(cas: 103-74-2COA of Formula: C7H9NO)
2-(2-Hydroxyethyl)pyridine(cas: 103-74-2) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. COA of Formula: C7H9NO