In 2016,Wang, Hongyue; Wang, Ze; Li, Shaoheng; Qiu, Yuntao; Liu, Bowen; Song, Zhiguang; Liu, Zhihui published 《Synthesis of novel thiazoline catalysts and their application in Michael addition reaction》.Chemical Research in Chinese Universities published the findings.Recommanded Product: 31106-82-8 The information in the text is summarized as follows:
Several novel chiral thiazoline catalysts containing thiazoline, thiourea and proline were efficiently synthesized from com. available L-cysteine. These ligands were subsequently applied to the asym. Michael reaction between cyclohexanone and various β-nitrostyrene. The result showed that the optimal catalyst for this reaction was 2-methylpyridine containing chiral thiazoline ligand , the organocatalyst with thiazoline, thiourea and chiral proline motif, which efficiently promoted the enantioselective conjugate addition of cyclohexanone to various nitroalkenes to yield the corresponding addition products in high to excellent yields with enantiomeric excess(e.e.) up to 95% and diastereoselectivity ratio(dr.) up to 99:1. The results came from multiple reactions, including the reaction of 2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8Recommanded Product: 31106-82-8)
2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Recommanded Product: 31106-82-8