On August 21, 2018, Wang, Xiaoqin; Zhao, Chuping; He, Minghua; Zhong, Zhiqian; Chen, Jiahe; Wang, Yanchun; Wang, Maoqin published a patent.Formula: C10H10N4 The title of the patent was Preparation of 3,3′-disubstituted bipyridine derivative as anti-Alzheimer’s disease drug. And the patent contained the following:
This invention provides 3,3′-disubstituted dipyridine derivatives I and II [wherein R = H, OH, halo, etc.; R1 = O(CH2)mCH3 or OH; m and n = independently 0-3; R2 = alkyl, one or more Me or Et substituted amino, etc.]. The title compounds can be used in preparing drugs for prevention and/or treatment of Alzheimer’s disease, vascular dementia or myasthenia gravis disease. The invention has the advantages of low biotoxicity, good safety, and broad application space in preparing anti-Alzheimer’s disease drugs. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Formula: C10H10N4
The Article related to bipyridine treatment alzheimer disease vascular dementia myasthenia gravis human, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Formula: C10H10N4