Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Synthetic Route of 16133-25-8.
Wei, Jingjing;Liang, Shuaishuai;Jiang, Lvqi;Mumtaz, Yasir;Yi, Wen-bin research published 《 Regioselective Chloro-thiolation of Alkenes with Sulfonyl Chlorides》, the research content is summarized as follows. A newly developed sulfonyl chlorides-based regioselective chloro-thiolation of alkenes has been disclosed, the reaction is compatible with a variety of functional groups and can be scaled up to the gram-scale with no loss in yield. The employment of readily available reactants, mild reaction conditions, and high regioselectivity makes this process very practical. Mechanistic studies revealed a possible free radical reaction pathway.
Synthetic Route of 16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.