Wei, Ningyi published the artcileImprovement and suggestion on the problems existing in the betahistine mesilate monograph, SDS of cas: 54856-23-4, the publication is Zhongguo Yaopin Biaozhun (2011), 12(5), 384-386, database is CAplus.
A method for determination of water in betahistine mesilate that was of hygroscopicity and thermal instability was established. HPLC, TLC, DSC purity, and hygroscopicity under varying relative humidity conditions were determined Loss on drying influenced on purity of betahistine mesilate. Determination of water by Karl Fischer should be instead of loss on drying in vacuum at 70 degree method. Loss on drying makes betahistine mesilate degraded. The Karl Fischer method is simple, accurate, and suitable for determination of water.
Zhongguo Yaopin Biaozhun published new progress about 54856-23-4. 54856-23-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Salt,Amine,Inhibitor,Inhibitor, name is N-Methyl-2-(pyridin-2-yl)ethan-1-amine dimethanesulfonate, and the molecular formula is C7H13NO2, SDS of cas: 54856-23-4.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem