An article Practical Method for Reductive Deuteration of Ketones with Magnesium and D2O WOS:000513082700046 published article about SELECTIVE REDUCTION; LABELED COMPOUNDS; HYDROGEN ISOTOPE; PRIMARY ALCOHOLS; DEUTERIUM; ACTIVATION; TRITIATION; DISCOVERY; SYSTEM; MILD in [Zhu, Nengbo; Su, Min; Wan, Wen-Ming; Li, Yajun; Bao, Hongli] Chinese Acad Sci, Ctr Excellence Mol Synth, Fujian Inst Res Struct Matter, State Key Lab Struct Chem,Key Lab Coal Ethylene G, Fuzhou 350002, Peoples R China in 2020.0, Cited 59.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. Formula: C12H9NO
alpha-Deuterated alcohols have important applications in pharmaceuticals and mechanism studies. Here, we report a new and practical strategy for the reductive deuteration of ketones using a Mg/BrCH2CH2Br/D2O system, which affords alpha-deuterated alcohols in good yields and with almost quantitative incorporation of deuterium. The synthetic value of this method has been demonstrated by the easy access to deuterated drugs or drug derivatives. This method may inspire the discovery of other deuterium-containing drugs.
Formula: C12H9NO. Welcome to talk about 91-02-1, If you have any questions, you can contact Zhu, NB; Su, M; Wan, WM; Li, YJ; Bao, HL or send Email.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem