Microwave irradiation induced synthesis of 2-amino-4,6-diarylpyridines was written by Wu, Ping;Cai, Xi-Mei;Yan, Chao-Guo. And the article was included in Youji Huaxue in 2006.HPLC of Formula: 17281-59-3 This article mentions the following:
Under microwave irradiation, N-cyanomethylpyridinium chloride reacted with chalcones in the presence of ammonium acetate and acetic acid to give 2-amino-4,6-diarylpyridines in high yields. 2-Aminoduiarylpyridines can also be prepared from one-pot reactions of N-cyanomethylpyridinium chloride with aromatic aldehydes and substituted acetophones. The structures of the products were characterized with 1H NMR, IR and HPLC-MS spectra. In the experiment, the researchers used many compounds, for example, 1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3HPLC of Formula: 17281-59-3).
1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·molâ? in pyridine vs. 150 kJ·molâ? in benzene). Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one CâH in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.HPLC of Formula: 17281-59-3