Name: 2,6-DibromopyridineIn 2020 ,《A novel approach for rhodium(III)-catalyzed C-H functionalization of 2,2′-bipyridine derivatives with alkynes: a significant substituent effect》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Wu, Shaonan; Wang, Zhuo; Bao, Yinwei; Chen, Chen; Liu, Kun; Zhu, Bolin. The article conveys some information:
The authors described a novel approach for the C-H functionalization of 2,2′-bipyridine derivatives with alkynes. DFT calculations and exptl. data showed a significant substituent effect at the 6-position of 2,2′-bipyridine, which weakened the adjacent N-Rh bond and provided the possibility of subsequent rollover cyclometalation, C-H activation, and functionalization.2,6-Dibromopyridine(cas: 626-05-1Name: 2,6-Dibromopyridine) was used in this study.
2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Name: 2,6-Dibromopyridine