Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. SDS of cas: 16133-25-8.
Xie, Feng;Lu, Guang-Peng;Xie, Rong;Chen, Qing-Hua;Jiang, Huan-Feng;Zhang, Min research published 《 MOF-Derived Subnanometer Cobalt Catalyst for Selective C-H Oxidative Sulfonylation of Tetrahydroquinoxalines with Sodium Sulfinates》, the research content is summarized as follows. Cobalt supported on nitrogen-doped carbon was prepared by deposition of cobalt into ZIF-8 followed by pyrolysis and used as a catalyst for the aerobic oxidative sulfonylation of 1,2,3,4-tetrahydroquinoxalines with sodium sulfinates in the presence of NH4I to yield arylsulfonylquinoxalines such as I (R = Ph, 4-MeC6H4, 4-MeOC6H4, 2-naphthyl, 2,4,6-Me3C6H2, 4-FC6H4, 2-FC6H4, 4-ClC6H4, 4-BrC6H4, 4-F3CC6H4, 3-pyridinyl, 2-thienyl, 8-quinolinyl, 3,5-dimethyl-4-isoxazolinyl, Me, Et, cyclopropyl). The supported cobalt catalyst was used six times with < 10% decrease in product yield.
SDS of cas: 16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.