Rh(
Rhodium-catalyzed inert C(sp3)-H activation/carbene insertion, which enables the construction of all-carbon quaternary centers, has been realized. Iodonium ylides are used as C1 synthons for efficient C-C bond formation with PhI being the only byproduct. A rhodacycle has been synthesized and proved to be the active intermediate. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Formula: C8H11N).
2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 锜?bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 锜?bonds. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Formula: C8H11N