Xin, Zhijun published the artcileStudy on N-(pyridin-4-yl) salicylamides as antimycobacterial agents, HPLC of Formula: 18437-58-6, the publication is Advanced Materials Research (Durnten-Zurich, Switzerland) (2013), 1371-1375, 6 pp., database is CAplus.
A series of N-(pyridin-4-yl) salicylamides derivatives were prepared through acylation of the corresponding acetylsalicyloyl chlorides with substituted 4-amino-pyridines. These compounds were evaluated in vitro for antimycobacterial activities against Mycobacterium tuberculosis (TB) and Mycobacterium avium (A) by the min. inhibitory concentrations (MIC) values. Eight of the compounds exhibited lower MIC against A than isoniazide (INH). Meanwhile, four of the compounds exhibited good anti-TB activity, when they were compared with INH. Antimycobacterial activities of N-(pyridin-4-yl) salicylamides were influenced by the balance between hydrophobicity and electron-withdrawing substituent effect on the Ph and pyridine ring. These studies show that these compounds might serve as prospective wide-spectrum antimycobacterial substances.
Advanced Materials Research (Durnten-Zurich, Switzerland) published new progress about 18437-58-6. 18437-58-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 4-Amino-2-picoline, and the molecular formula is C24H12, HPLC of Formula: 18437-58-6.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem