Catalytic activity of sterically hindered heterocyclic tertiary amines in thiosemicarbazide formation was written by Yanchuk, N. I.. And the article was included in Russian Journal of General Chemistry (Translation of Zhurnal Obshchei Khimii) in 1998.SDS of cas: 644-98-4 This article mentions the following:
Kinetics of the reaction of diphenylphosphinic hydrazide with Ph isothiocyanate in benzene at 25° in the presence of 2-alkyl-substituted pyridines and N-methylbenzimidazoles were studied. Steric and inductive components of the nucleophilicity of these tertiary amines were determined The catalytic activity of pyridines was more sensitive to steric demand of the catalytic center compared with that of benzimidazoles. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4SDS of cas: 644-98-4).
2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. SDS of cas: 644-98-4