Pyridine is colorless, but older or impure samples can appear yellow. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. SDS of cas: 31181-90-5.
Yang, Chaofu;Feng, Yan;Yang, Xu;Sun, Mingxia;Li, Zhenwang;Liu, Xuan;Lu, Liang;Sun, Xianyu;Zhang, Jiwen;He, Xinhua research published 《 Synthesis and evaluation of 4-(1,3,4-oxadiazol-2-yl)-benzenesulfonamides as potent carbonic anhydrase inhibitors》, the research content is summarized as follows. Human carbonic anhydrases (hCA) I and II are targets for agents treating acute altitude sickness. Twenty-one 4-(1,3,4-oxadiazol-2-yl) benzenesulfonamides were synthesized and screened against these two isoforms. 4-(5-(2,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide , 4-(5-(2,3-dichlorophenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide, 4-(5-(4-(dimethylamino) phenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide, 4-(5-(naphthalen-2-yl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide were more potent against both hCA I and II than clin. drug AAZ. In particular, the value of compound 4-(5-(2,4-dimethylphenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide with hCA I (18.08 nM) was over 84-fold more than of AAZ with hCA I. The data of docking simulations were also in accord with the tendency of inhibitive activities. Furthermore, methanesulfonate of 4-(5-(4-(dimethylamino) phenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide, showed better anti-hypoxia activity than AAZ in vivo, making it interesting lead compound
SDS of cas: 31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.
5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.