Formula: C5H5BrN2On October 4, 2019 ,《Silver-Mediated Trifluoromethoxylation of (Hetero)aryldiazonium Tetrafluoroborates》 was published in Organic Letters. The article was written by Yang, Yu-Ming; Yao, Jian-Fei; Yan, Wei; Luo, Zhuangzhu; Tang, Zhen-Yu. The article contains the following contents:
Here we report a silver-mediated trifluoromethoxylation of (hetero)aryldiazonium tetrafluoroborates by converting an aromatic amino group into an OCF3 group. This method, which can be considered to be a trifluoromethoxylation variation of the classic Sandmeyer-type reaction, uses readily available aryl and heteroaromatic amines as starting materials and AgOCF3 as trifluoromethoxylating reagents. The broad substrate scope and simple, mild reaction condition made this transformation a valuable method in constructing aryl-OCF3 bonds. In addition to this study using 2-Bromopyridin-3-amine, there are many other studies that have used 2-Bromopyridin-3-amine(cas: 39856-58-1Formula: C5H5BrN2) was used in this study.
2-Bromopyridin-3-amine(cas: 39856-58-1) belongs to anime. Amine, any member of a family of nitrogen-containing organic compounds that is derived, either in principle or in practice, from ammonia (NH3). Naturally occurring amines include the alkaloids, which are present in certain plants; the catecholamine neurotransmitters (i.e., dopamine, epinephrine, and norepinephrine); and a local chemical mediator, histamine, that occurs in most animal tissues.Formula: C5H5BrN2