Recommanded Product: 500-22-1. Recently I am researching about FIBROSIS, Saw an article supported by the Veterans Affairs Merit ReviewUS Department of Veterans Affairs [1I01BX002025]; National Institute of HealthUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USA [R01-DK119212, P30-DK114809]; VA Senior Research Career Scientist award; William K. Warren Foundation; Chair in Medicine. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Jeffries, DE; Borza, CM; Blobaum, AL; Pozzi, A; Lindsley, CW. The CAS is 500-22-1. Through research, I have a further understanding and discovery of 3-Pyridinecarboxaldehyde
Herein, we report the discovery of a potent and selective dual DDR1/2 inhibitor, 7e (VU6015929), displaying low cytotoxicity, good kinome selectivity, and possessing an acceptable in vitro DMPK profile with good rodent in vivo pharmacokinetics. VU6015929 potently blocks collagen-induced DDR1 activation and collagen-IV production, suggesting DDR1 inhibition as an exciting target for antifibrotic therapy.
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Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem