The author of 《Mitochondrion-targeted two-photon probes: Real-time monitoring endogenous GSH via situ reaction in Hela cells》 were Zhang, Huihui; Zhang, Gaojian; Liu, Gang; Xia, Ying; Fang, Min; Zhu, Xiaojiao; Wu, Zhichao; Li, Xiaowu; Yang, Xingyuan; Zhou, Hongping. And the article was published in Dyes and Pigments in 2019. Application In Synthesis of 2-(Bromomethyl)pyridine hydrobromide The author mentioned the following in the article:
Mitochondria and glutathione (GSH) play crucial roles in human pathologies. To better understand the disease mechanisms, two-photon fluorescence probes responding to mitochondria and glutathione were urgently pursued. Here, a series of two-photon fluorescence probes (5a, 5b and 5c) were prepared, which could detect GSH as well as target mitochondria. The probes delivered high and rapid selectivity towards GSH among the various biothiols and qual. monitored the endogenous cellular GSH in real-time via a two-photon laser confocal fluorescence microscopy. Furthermore, the theor. understanding of high selectivity in two-photon fluorescence probes were also performed. The combined results demonstrated that the probes would function as efficient tools in bio-imaging and biol. diagnosis. The experimental part of the paper was very detailed, including the reaction process of 2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8Application In Synthesis of 2-(Bromomethyl)pyridine hydrobromide)
2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Application In Synthesis of 2-(Bromomethyl)pyridine hydrobromide