Construction and regulation of imidazo[1,5-a]pyridines with AIE characteristics via iodine mediated Csp2-H or Csp-H amination was written by Zhang, Jun;She, Mengyao;Liu, Lang;Liu, Mengdi;Wang, Zhaohui;Liu, Hua;Sun, Wei;Liu, Xiaogang;Liu, Ping;Zhang, Shengyong;Li, Jianli. And the article was included in Chinese Chemical Letters in 2021.Related Products of 91-02-1 This article mentions the following:
The widespread applications of aggregation-induced emission luminogens (AIEgens) inspire the creation of AIEgens with novel structures and functionalities. In this work, we focused on the direct and efficient synthesis of a new type of AIEgens, imidazo[1,5-a]pyridine derivatives, via iodine mediated cascade oxidative Csp2-H or Csp-H amination route from phenylacetylene or styrenes under mild conditions. The resulted compounds showed excellent AIE characteristics with tunable maximum emissions, attractive bioimaging performance, and potential anti-inflammatory activity, which exert broad application prospects in material, biol., medicine, and other relevant areas. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1Related Products of 91-02-1).
Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Related Products of 91-02-1