In 2016,Zhang, Mengjia; Weng, Zhiqiang published 《Copper-Mediated Trifluoromethylthiolation of Heteroaryl Bromides》.Advanced Synthesis & Catalysis published the findings.Related Products of 29682-15-3 The information in the text is summarized as follows:
An efficient protocol for the copper-mediated trifluoromethylthiolation of heteroaryl bromides has been achieved using the copper complex (bpy)Cu(SCF3) as trifluoromethylthiolation reagent. This procedure provides a straightforward synthetic method for heteroaryl trifluoromethyl sulfides from readily available, simple starting materials. The reaction demonstrates a broad substrate scope and tolerates a wide array of functional groups, including nitrile, ester, chloro, nitro, or methoxy substituents. The synthesis of the target compounds was achieved by a reaction of (2,2′-bipyridine-κN1,κN1′)(1,1,1-trifluoromethanethiolato-κS)copper with aryl bromides, such as 2-bromopyridine derivatives, 3-bromopyridine derivatives, 4-bromopyridine derivatives, bromoquinoline derivatives, 2-bromoquinoxaline, 2-bromopyrimidine, 2-bromothiazole derivatives, 6-(bromo)imidazo[1,2-a]pyridine. After reading the article, we found that the author used Methyl 5-bromopicolinate(cas: 29682-15-3Related Products of 29682-15-3)
Methyl 5-bromopicolinate(cas: 29682-15-3) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Related Products of 29682-15-3