Zhang, Xiao; Yang, Chao; Gao, Han; Wang, Lei; Guo, Lin; Xia, Wujiong published their research in Organic Letters in 2021. The article was titled 《Reductive Arylation of Aliphatic and Aromatic Aldehydes with Cyanoarenes by Electrolysis for the Synthesis of Alcohols》.Application In Synthesis of 4-Cyanopyridine The article contains the following contents:
An electroreductive arylation reaction of aliphatic and aromatic aldehydes as well as ketones with electro-deficient (hetero)arenes is described. A variety of cyano(hetero)arenes and carbonyl compounds, especially aliphatic aldehydes, have been examined, providing secondary and tertiary alcs. in moderate to good yields. Mechanistic studies, including cyclic voltammetry (CV), ESR (EPR), and divided-cell experiments, support the generation of aliphatic ketyl radicals and persistent heteroaryl radical anions via cathodic reduction followed by radical-radical cross-coupling. In the experimental materials used by the author, we found 4-Cyanopyridine(cas: 100-48-1Application In Synthesis of 4-Cyanopyridine)
4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Application In Synthesis of 4-Cyanopyridine