Zhang, Youcan published the artcileCopper-catalyzed carbonylative synthesis of pyrrolidine-containing amides from γ,δ-unsaturated aromatic oxime esters, Related Products of pyridine-derivatives, the main research area is pyrrolidine containing amide preparation regioselective copper catalyst; unsaturated aromatic oxime ester amine carbonylative cyclization.
A new method of low-cost copper-catalyzed carbonylative cyclization for preparing pyrrolidine-containing amides I (R = H, R’ = t-Bu, Ph, 2-Py, etc; R1 = Me, Et, Ph, R2 =Me, Allyl, CHC6H5; Ar = Ph, 3-MeC6H4, 2-thiophenenyl, 2-Naph, etc.; R3, R4 = H, Me;) from γ,δ-unsaturated aromatic oxime esters II and amines has been described. A range of readily available amines were examined, including primary, secondary, and heterocycle amines, giving over 60 examples of targeted N-heterocycle substituted amides with broad functional group tolerance, good chem. selectivity and moderate to excellent yields.
Organic Chemistry Frontiers published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 133627-45-9 belongs to class pyridine-derivatives, name is 2-Chloro-4-methylpyridin-3-amine, and the molecular formula is C6H7ClN2, Related Products of pyridine-derivatives.