In 2017,Zhao, Jiannan; Brosmer, Jonathan L.; Tang, Qingxuan; Yang, Zhongyue; Houk, K. N.; Diaconescu, Paula L.; Kwon, Ohyun published 《Intramolecular Crossed [2+2] Photocycloaddition through Visible Light-Induced Energy Transfer》.Journal of the American Chemical Society published the findings.Name: 2-Bromonicotinaldehyde The information in the text is summarized as follows:
Herein, we present the intramol. [2+2] cycloadditions of dienones promoted through sensitization, using a polypyridyl iridium(III) catalyst, to form bridged cyclobutanes [e.g., I → II (93%)]. In contrast to previous examples of straight [2+2] cycloadditions, these efficient crossed additions were achieved under irradiation with visible light. The reactions delivered desired bridged benzobicycloheptanone products with excellent regioselectivity in high yields (up to 96%). This process is superior to previous syntheses of benzobicyclo[3.1.1]heptanones, which are readily converted to B-norbenzomorphan analogs of biol. significance. Electrochem., computational, and spectroscopic studies substantiated the mechanism of triplet energy transfer and explained the unusual regiocontrol. In the part of experimental materials, we found many familiar compounds, such as 2-Bromonicotinaldehyde(cas: 128071-75-0Name: 2-Bromonicotinaldehyde)
2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Name: 2-Bromonicotinaldehyde